Epidermolysis bullosa acquisita in Dogs

Category: Skin & Connective Tissue
Breeds documented: 1
Published sources: 2

Overview

Blisters and deep sores develop when the immune system attacks proteins that help attach the outer skin to the tissue beneath. This rare disease, epidermolysis bullosa acquisita, can affect both the skin and moist surfaces such as the mouth. Sores often occur on the ears, lips, groin and paw pads. Affected dogs may be painful, lose interest in food and seem generally unwell.

Signs to watch for

Fluid-filled blisters that leave deep, open sores
Sores inside the mouth or on the lips
Blisters or crusts on the ears and areas that rub
Raw paw pads, sometimes with peeling skin
Pain, low energy or reduced appetite

Many reported dogs developed signs when young, but adult onset also occurs.

When to get help Contact your vet promptly if blisters or open sores appear, especially in the mouth or paws.

Diagnosis and tests

Vets examine the pattern of sores and take skin samples, called biopsies, to look for separation beneath the outer skin layer. Special tissue stains can help support the diagnosis. Where available, tests for immune proteins that attack the skin's attachments can help distinguish this disease from similar blistering disorders.

Breeds with documented risk

1 breed

By breed size

1 Giant

Great DaneGiant · Working Group

Inheritance

Not yet known
None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.