Golden Retriever Progressive Retinal Atrophy 1 in Dogs

Category: Eye
Breeds documented: 1
Published sources: 6

Overview

In GR-PRA1, an inherited change in the SLC4A3 gene is linked to gradual damage to the retina, the light-sensitive lining at the back of the eye. Both eyes are affected, and vision loss can eventually become complete. Like other forms of progressive retinal atrophy, it often affects night vision first. The disease itself is not painful, and many dogs adjust well as their sight changes.

Signs to watch for

Hesitating before entering dark rooms
Bumping into objects in unfamiliar places
Reluctance to go down steps
Pupils that look larger than usual

Signs of GR-PRA1 commonly appear around six years of age.

When to get help Book a vet visit if your dog begins struggling to see in dim light.

Diagnosis and tests

A vet examines the retina in both eyes for changes consistent with progressive retinal atrophy. An eye specialist may use electroretinography, a test of the retina's electrical response to light, when further testing is needed. A DNA test for GR-PRA1 can identify dogs carrying the SLC4A3 variant and those at risk of this form of disease.

Breeds with documented risk

1 breed

By breed size

1 Large

Golden RetrieverLarge · Sporting Group

Inheritance

Not yet known
None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.