Platelet Factor X Receptor Deficiency in Dogs

Category: Blood
Breeds documented: 1
Published sources: 4

Overview

This inherited platelet disorder disrupts the surface where clotting proteins work together to build a stable blood clot. It is also called Scott syndrome. An affected dog's platelet count and routine clotting tests can still look normal. Bleeding and bruising after surgery are common reasons for investigation, though some dogs have nosebleeds or bleeding into deeper tissues.

Signs to watch for

Unusual bleeding after surgery or tooth removal
Bruising or soft swelling around an operation site
Repeated nosebleeds
Limping with swelling or bruising in a limb

It may first be recognized in young adults, often after surgery.

Emergency Go to an emergency vet now if your dog is bleeding heavily.

Diagnosis and tests

Routine blood tests alone can miss this disorder because platelet numbers and standard clotting times may be normal. Vets first exclude more common causes of abnormal bleeding. Confirmation needs specialist tests of the platelet surface's ability to support clotting. These can measure clotting protein use and assess changes on activated platelets.

Breeds with documented risk

1 breed

By breed size

1 Large

German ShepherdLarge · Herding Group

Inheritance

Not yet known
None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.