Hypersensitivity to potentiated antimicrobial sulfonamides in Dogs

Category: Immune System
Breeds documented: 4
Published sources: 6

Overview

An unpredictable reaction to certain prescribed antibiotics can affect several parts of the body. This delayed reaction may involve the skin, joints, eyes, liver or blood cells. It can occur after a dog has been receiving treatment for days or weeks. The range and severity of problems vary, and dogs with liver involvement or low platelet counts may have a poorer outcome.

Signs to watch for

New skin rashes or sores
Limping or painful joints
Facial swelling

In one study, affected dogs were 6 months to 14 years old; signs began 5 to 36 days after treatment started.

When to get help Contact the prescribing vet promptly if new skin sores, limping or facial swelling develop.

Diagnosis and tests

Vets investigate the timing of new signs in relation to a dog's antibiotic treatment. Blood tests can identify liver changes or changes in blood cells, while the examination may reveal joint or skin problems. Other plausible causes must be considered before a medication reaction is suspected.

Breeds with documented risk

4 breeds

By breed size

1 Small
1 Medium
2 Large

RottweilerLarge · Working Group
Doberman PinscherLarge · Working Group
Miniature SchnauzerSmall · Terrier Group
SamoyedMedium · Working Group

Inheritance

Not yet known
None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.