Primary Hyperparathyroidism in Dogs

Category: Hormonal
Inheritance: Autosomal dominant
Breeds documented: 1
Published sources: 2

Overview

The parathyroid glands in the neck help regulate the amount of calcium in the blood. When one or more glands release too much parathyroid hormone, blood calcium can rise above normal. This is usually caused by a noncancerous growth in a gland. Some dogs have few outward signs, while others develop thirst, weakness or urinary problems. Persistently high calcium can damage tissues, particularly the kidneys.

Signs to watch for

Drinking more than usual
Urinating more often
Weakness or unusually low energy
Reduced appetite
Vomiting or losing weight

Usually develops in older dogs, most often after age 7.

When to get help Book a vet visit promptly for increased thirst, frequent urination or unexplained weakness.

Diagnosis and tests

Vets measure blood calcium alongside parathyroid hormone, because the results need to be interpreted together. High calcium with hormone levels that have not fallen appropriately supports the diagnosis. Ultrasound of the neck helps locate an abnormal gland. A genetic screening test is available for the inherited form in Keeshonds.

Breeds with documented risk

1 breed

By breed size

1 Medium

KeeshondMedium · Non-Sporting Group

Inheritance

Autosomal dominant
Keeshond
One copy of the variant, from either parent, is enough to put a dog at risk. On average, an affected dog passes the variant to half of its puppies. Males and females are affected equally.
As stated by OMIA

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.