Progressive Retinal Atrophy 1 in Dogs

Category: Eye
Breeds documented: 1
Published sources: 6

Overview

The CNGB1 form of progressive retinal atrophy affects the retina, the eye's light-sensitive lining. It has been documented in Papillons and Phalenes and is associated with an inherited change in the CNGB1 gene. Cells used for dim-light vision lose function first, so trouble seeing at night can be an early clue. Progression can be very slow, with useful daytime vision lasting much longer.

Signs to watch for

Trouble navigating in dim light
Hesitation before going outside after dark
Larger-looking pupils
Clumsiness in unfamiliar surroundings

In Papillons, an average onset of 5.6 years has been reported.

When to get help Book a vet visit if your dog starts having difficulty moving around in dim light.

Diagnosis and tests

A veterinary eye examination looks for progressive damage to the retina. A specialist may use electroretinography, which measures electrical activity in response to light, to assess retinal function. A DNA test is available for this variant. Testing for the CNGB1 variant helps identify this inherited form, while eye examination assesses current changes in vision.

Breeds with documented risk

1 breed

By breed size

1 Toy

PapillonToy · Toy Group

Inheritance

Not yet known
None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.