Stargardt Disease in Dogs

Category
Eye
Breeds documented
1
Published sources
5

Overview

An inherited ABCA4 gene change can lead to slow degeneration of the retina, the light-sensitive tissue at the back of the eye. The disease affects cells involved in daytime and dim-light vision. Visual problems may not be obvious until later life. Some affected dogs retain sight, so complete blindness is not inevitable.

Signs to watch for

  • Reduced ability to see in daylight.
  • Difficulty seeing in dim light.
  • Pupils that stay unusually large in daylight.

Noticeable vision problems often develop in middle or old age; young dogs may seem normal.

When to get help Book a vet visit when you notice changes in your dog's vision.

Diagnosis and tests

DNA testing can identify the ABCA4 variant associated with canine Stargardt disease. A specialist eye examination assesses the retina, while an electroretinogram measures its response to light. Apparently normal vision in a young dog does not exclude the variant, making genetic testing useful before breeding.

Breeds with documented risk

1 breed

By breed size
  • 1 Large

Inheritance

  • Not yet known

    None of the sources we use states how this is inherited in dogs yet.

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.

Sources

  1. journals.plos.org
  2. jstage.jst.go.jp
  3. vet.tufts.edu
  4. Labrador Retriever: pubmed.ncbi.nlm.nih.gov
  5. Labrador Retriever: omia.org