Pyruvate Dehydrogenase Deficiency in Dogs

Category
Metabolic
Breeds documented
2
Published sources
3

Breeds with documented risk

2 breeds

By breed size
  • 2 Medium

Inheritance

  • Autosomal recessive

    A dog is affected only if it inherits two copies of the gene variant, one from each parent. A dog with one copy is a carrier: usually healthy, but able to pass the variant on. When two carriers are bred, on average one puppy in four is affected. A DNA test can tell clear, carrier and at-risk dogs apart.

    As stated by OMIA

We've gathered what published sources say about this condition, so you can talk it through with your vet. It isn't veterinary advice: you and your vet know your dog best.

Sources

  1. OMIA: Pyruvate dehydrogenase deficiency: omia.org
  2. Clumber Spaniel: pubmed.ncbi.nlm.nih.gov
  3. Clumber Spaniel: omia.org